If you really want the best atmosphere from your sets, experiment with bitrates on each track before playing out. I mean not every track suits high quality encoding. Take Kuffdam & Plant - Dream Makers for example. Sounds deep and psychadelic at 80K, yet sounds cold and tinny at the full 320K release quality. Much clearer, sure, but is that what you want every time? Depends what youre going for. I think this is territory DJs are yet to explore fully; a mixer cant fully emulate a low quality sound file.
What im saying is low quality doesnt necessarily equal bad or wrong.
Forest Gump chumps get clumps of nuttin' for nuttin'